Figure 1. Drosophila Dalmatian protein is a functional hybrid of the vertebrate cohesin regulators shugoshin and sororin.

(A) The tripartite cohesin ring and its accessory proteins are conserved between vertebrates and Drosophila, but the sororin and shugoshin regulators are combined in a single protein called Dalmatian (Dmt) in flies. (B) Domain structure of Dalmatian indicating the binding domains mapped by Yamada et al (2017).