Figure 1. Nitrogen starvation leads to transcriptional reprogramming of central carbon metabolism.

1. Overview of reprogramming of primary metabolism as visualized by the MapMan program and using the normalized RNA‐Seq data. Points represent the log₂ fold change in gene expression in nitrogen‐starved cells 20 h after medium change versus control cells at the same time point. Red and blue indicate gene induction and repression, respectively.
2. Overview of amino acid degradation and central carbon metabolism (adapted from Hockin et al, 2012 and Obata et al, 2013). Not all reaction products are shown, and some arrows represent more than one reaction. Measured metabolites are indicated by rectangles of which the colours indicate relative log₂ fold change in nitrogen‐starved versus control cells at 20 h. Pathways are indicated by ovals. Coloured boxes next to arrows indicate mRNA expression changes in log₂ fold change of FPKM values of the nitrogen‐starved sample versus the control sample at 20 h.