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. 2017 Apr 28;9(6):835–851. doi: 10.15252/emmm.201607176

Figure EV4. RANKL treatment early after BMT boosts peripheral T‐cell reconstitution optimally in an LTα‐dependent manner.

Figure EV4

Histograms show numbers of total cells and CD4+ and CD8+ T cells as well as CD4+Foxp3+ Tregs from CD45.1 donor origin in the spleen of WT CD45.1:WT and WT CD45.1:LTα−/− mice treated with GST or RANKL proteins at d2, d4, and d6 pBMT and analyzed at d21 and d65 pBMT. pBMT: post‐bone marrow transplantation. Data are shown as mean ± SEM and are pooled of three independent experiments with similar results (n = 3–5 mice per group). *P < 0.05; **P < 0.01; ***P < 0.001; one‐tailed Mann–Whitney U‐test. Exact P‐values are provided in Appendix Table S2.