Figure 7. Beneficial effects mediated by RANKL treatment on thymic regeneration after BMT require LTα expression in aged mice.

• A, B
  Numbers of total TECs, cTECs, mTECs (A), and TEPC‐enriched cells (B) were analyzed at d21 upon BMT in the thymus from WT CD45.1:WT and WT CD45.1:LTα^−/− chimeras of 6–8 months of age treated with GST or RANKL proteins.
• C, D
  Numbers of total thymic cells, thymocyte subsets (C), and ETPs (D) of CD45.1 origin.

Data information: Data are shown as mean ± SEM and are pooled of two independent experiments with similar results (n = 3 mice per group). *P < 0.05; one‐tailed Mann–Whitney U‐test. Exact P‐values are provided in Appendix Table S2.