Table 7.
Upcoming trials.
| Clinical trial number | Study type | Target number | Clinical Setting |
|---|---|---|---|
| ACTRN12614000093684 | (LoDoCo 2 trial) | Randomized double-blind, placebo control trial | |
| 3000 | - To determine the effect of low dose [0.5mg/day] colchicine on the composite of clinical events including [1] acute coronary syndrome - troponin positive acute coronary syndrome [myocardial infarction] or unstable angina with angiographic evidence of disease progression, [2] sudden cardiac death or non-fatal out of hospital arrest and [3] non-cardio-embolic ischemic stroke in patients with documented but clinically stable coronary artery disease. | NCT02162303 | |
| (COPLET trial) | Randomized double-blind, placebo control trial | 106 | - To assess the effects of colchicine on vascular inflammation measured by metabolic imaging and plasma biomarkers in patients with atherosclerotic vascular disease. |
| NCT01906749 | (COACS trial) | Multicenter, Randomized double-blind, placebo control trial | |
| 500 | - To assess the effect of low-dose colchicine (0.5mg/day) on overall mortality, new coronary syndromes, and ischemic stroke at 2 years after an acute coronary syndrome. | NCT01709981 | Randomized double-blind, placebo control trial |
| 400 | - To characterize a potential mechanism of benefit in patients undergoing percutaneous coronary intervention (PCI) by evaluating the effects of colchicine on soluble and leukocyte surface markers after PCI. | - To determine the effects of colchicine on peri-procedural myonecrosis and myocardial infarction. |
Randomized double-blind, placebo control trial
60
- To access effect of colchicine on C-reactive protein in chronic atrial fibrillation and following atrial fibrillation ablation.
ACTRN12613001345774
Randomized double-blind, placebo control trial
520
- To evaluate the effect of colchicine in preventing postoperative atrial fibrillation after cardiac surgery.