Targeted quantitative mitochondrial proteomics of proteins involved in (A) fatty acid β-oxidation; (B) tricarboxylic acid (TCA) cycle; and (C) oxidative phosphorylation, in livers of rats receiving normal water (CON), a 13% (w/v) glucose solution (GLU), a 13% (w/v) fructose solution (FRUC), or a 0.4% (w/v) aspartame solution (n = 6 per diet group). Gene names and corresponding protein names: Cpt1a: Carnitine O-palmitoyltransferase 1A; Etfa: Electron-transfer-flavoprotein, alpha polypeptide; Etfb: Electron-transfer-flavoprotein, beta polypeptide; Etfdh: Electron-transferring-flavoprotein dehydrogenase; Echs1: Enoyl CoA hydratase, short chain, 1; Hadha: Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Hadhb: Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit; Pdha1: Pyruvate dehydrogenase E1 component subunit alpha; Dlat: Dihydrolipoamide S-acetyltransferase; Aco2: Aconitase 2; Ogdh: Oxoglutarate (alpha-ketoglutarate) dehydrogenase; Sucla2: Succinyl-CoA ligase [ADP-forming] subunit beta; Suclg1: Succinate-CoA ligase, alpha subunit; Suclg2: Succinate-CoA ligase, beta subunit; Slc25a1: Solute carrier family 25, member 1; Slc25a3: Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3; Slc25a5: Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 5. Data are expressed as means ± SEM. * p < 0.05 vs. CON; †
p < 0.05 vs. ASP; §
p < 0.05 vs. GLU.