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. 2017 May 18;9(5):512. doi: 10.3390/nu9050512

Figure 4.

Figure 4

Effect of RBS and DOX on sleep-wake profiles in C57BL/6N mice. (a) Representative EEG and EMG signals, and corresponding hypnograms in a mouse treated with RBS or DOX; (b) Effects of RBS and DOX on sleep latency; (c) Amounts of NREMS and REMS during the 3 h period after administration of RBS or DOX. Grey bars indicate the baseline day (vehicle). Each value represents the mean ± SEM of each group (n = 7–8). * p < 0.05, ** p < 0.01, significantly different from vehicle (unpaired Student’s t-test). RBS, rice bran supplement; DOX, doxepin hydrochloride; EEG, electroencephalogram; EMG, electromyogram; Wake, wakefulness; REMS, rapid eye movement sleep; NREMS, non-REMS; NS, no significance.