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. 2017 May 18;9(5):512. doi: 10.3390/nu9050512

Figure 7.

Figure 7

Effects of the GABAA-BZD receptor antagonist, FLU, on changes in sleep latency (a) and sleep duration (b) in ICR mice treated with DZP (2 mg/kg) and RBS (1000 mg/kg). Drugs were administered (p.o.) to mice 45 min before the injection of pentobarbital (45 mg/kg, i.p.). FLU (8 mg/kg, i.p.) was injected 10 min before the administration of test samples. Each column represents mean ± SEM (n = 10). ** p < 0.01, significant difference when compared to the CON group (Dunnett’s test). ## p < 0.01, significant difference between treatment with FLU and treatment without FLU (unpaired Student’s t-test). CON, control; DZP, diazepam; FLU, flumazenil; NS, not significant; RBS, rice bran supplement.