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. 2017 May 31;18:10. doi: 10.1186/s12858-017-0083-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Comparison of PTP1B and DUSP5 PD. a Structural overlay of PTP1B and DUSP5 PD(WT), based on crystal structures with pdb codes 3CWE (PTP1B with a phosphonic acid inhibitor bound) and 2G6Z (DUSP5 PD), using Chimera. b Primary sequence alignment was done using Clustal Omega pairwise alignment and guide tree algorithm [37], which indicated an extremely low percent identity of 9.5%