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. 2017 May 31;19:114. doi: 10.1186/s13075-017-1325-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Quantification of ED1⁺ and ED2⁺ synovial macrophages in knee sections of control and treated rats. a ED1⁺ synovial macrophages, 6 days after the third boost, of control rats (black bars) and 2 × -MTX (dark grey) and 4 × -MTX (light grey) rats. b ED2⁺ synovial macrophages, 6 days after the third boost, of control rats (black bars) and 2 × -MTX (dark grey) and 4 × -MTX (light grey) rats. Values represent mean number of macrophages counted in predefined areas of the synovium. Error bars indicate SD. MTX methotrexate, SD standard deviation