Fig. 5.

Categorical body weight change and mean body weight loss in the BLOOM-DM trial. a Proportion of patients who lost ≥5 or ≥10% of body weight from baseline to week 52 using the modified intent to treat (MITT) population (left panel) or the completers population (right panel). Lorcaserin 10 mg BID red bars; lorcaserin 10 mg QD blue bars; placebo green bars. Values are proportion ± 95% confidence interval. *P < 0.001 as compared to placebo. b Percent change in body weight from baseline to each study visit, using the MITT population (left panel) or the completers population (right panel). Lorcaserin 10 mg BID red triangles with solid line; lorcaserin 10 mg QD blue circles with dashed line; placebo green diamonds with dashed line. Values are mean ± SEM. BID, twice daily; QD, once daily

Adapted from O’Neil et al. [49]