Table 2.

Relationship between serum leptin, BMI, and insulin resistance

Obesity level	Subjects n	Serum leptin	BMI			HOMA-IR
		Mean (SD)	Mean (SD)	r	P	Mean (SD)	r	P
Class I	27	33.9 (2.1)	32.8 (1.3)	0.15	0.50	2.6 (1.7)	0.18	0.42
Class II	24	38.8 (1.6)	37.4 (1.3)	0.31	0.16	2.8 (1.4)	0.36	0.11
Class III (morbid obesity)	29	50.1 (1.8)	46.3 (7.2)	0.27	0.008*	3.5 (2.6)	0.52	0.004*
Class III after controlling for BMI	29	50.1 (1.8)				3.5 (2.6)	0.46	0.014*

*means p<0.05 is statistically significant. SD=Standard deviation, HOMA-IR=Homeostasis model assessment insulin resistance, BMI=Body mass index