Figure 7.

States and weights for a MWC enzyme with a competitive inhibitor. While the substrate S (dark red) can be transformed into product, the inhibitor C (light blue) can occupy the substrate binding site but cannot be catalyzed. As seen with the allosteric regulator in section 2.3, the competitive inhibitor contributes a factor $\frac{[\mathrm{C}]}{C_{\mathrm{D}}}$ to the statistical weight of a state where C_D is the inhibitor’s dissociation constant.