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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
The surgery procedure for bone regeneration with a pig critical-sized mandible defect model. (A) A full-thickness 3cm × 3 cm bone defect was created at the lower margin of the mandibular body of a pig, which was reconstructed by (B) a tissue-engineered PCL/PRP/PASCs construct.