TABLE 6.

S. Typhimurium isolates with qnr and/or oqx genes and/or point mutations in gyrA and/or gyrB and/or parC^a

Isolate	S/I/R status		qnr and/or oqx gene(s) detected	Point mutationb detected in:
	NAL	CIP		gyrA	gyrB	parC
BOV_TYPH_NY_12_R8_9801	S	S	None	1641: T→G	WT	WT
BOV_TYPH_NY_12_R8_9815	S	S	None	1641: T→G	WT	WT
BOV_TYPH_NY_12_R8_9832	S	S	None	1641: T→G	WT	WT
HUM_TYPH_NY_11_R8_8073	S	S	None	WT	2202: G→A	WT
HUM_TYPH_NY_12_R9_0042	S	S	None	WT	2202: G→A	WT
HUM_TYPH_WA_08_R9_3269	I	S	qnrS	WT	WT	1713: C→T
HUM_TYPH_WA_08_R9_3270	R	I	oqxA, oqxB	Asp87Tyr	WT	1713: C→T
				259: G→T
HUM_TYPH_WA_09_R9_3271	S	S	None	WT	759: A→G	WT
HUM_TYPH_WA_10_R9_3273	R	S	oqxA, oqxB	Ser83Tyr	WT	1713: C→T
				248: C→A
HUM_TYPH_WA_10_R9_3274	I	S	qnrB	WT	WT	WT
HUM_TYPH_WA_11_R9_3275	R	S	oqxA, oqxB	Asp87Asn	WT	1713: C→T
				259: G→A
HUM_TYPH_WA_11_R9_3276	R	S	None	Asp87Asn	WT	1713: C→T
				259: G→A
HUM_TYPH_WA_12_R9_3277	S	S	None	WT	WT	1713: C→T

^aNo point mutations were detected in parE.

^bSynonymous point mutations resulting in no amino acid change are shown as position nt→nt (e.g., 259: G→A); amino acid substitutions (for gyrA or gyrB and parC) are formatted as “position: reference base → alternate base”; WT, gene with no mutations.