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. 2017 Apr 7;13(6):4463–4468. doi: 10.3892/ol.2017.6012

Figure 2.

Figure 2.

mRNA expression of AURKA, AURKB, AURKC, DLGAP5, CKAP5, KIF11, TPX2, TTK, TUBB and TUBB3 genes in SqCCL and AdC of the lung. Comparison between histology types demonstrated that the mRNA expression levels of the AURKA, AURKB, DLGAP5, KIF11, TPX2, TTK and TUBB genes in SqCCL tumours are significantly higher than those in AdC tumours. P-values were calculated using a Mann-Whitney U test and adjusted for multiple comparisons by Bonferroni correction. RQ values were calculated using RNA from the non-tumorigenic immortalised human bronchial epithelial cell line HBEC-3KT as a calibrator. Larger circles represent outlier values (>1.5x interquartile range); smaller circles represent extreme values (>3x interquartile range). AURK, Aurora kinase; DLGAP5, discs large-associated protein 5; CKAP5, cytoskeleton-associated protein 5; KIF11, kinesin-like protein 11; TPX2, microtubule nucleation factor TPX2; TTK, TTK protein kinase; TUBB, tubulin β; SqCCL, squamous cell carcinoma of the lung; AdC, adenocarcinoma; RQ, relative quantification.