Table II.
Univariate and multivariate Cox's proportional hazard regression analyses of potential predictors of overall survival among the study patients.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Covariates | HR (95% CI) | P-value | HR (95% CI) | P-value |
| AURKA mRNA | 1.79 (1.16–2.77) | 0.009 | 1.81 (1.16–2.84) | 0.009 |
| Age | 1.02 (1.00–1.05) | 0.066 | 1.03 (1.00–1.06) | 0.020 |
| Tumour stage | ||||
| 1 | Reference | Reference | Reference | Reference |
| 2 | 2.82 (1.35–5.86) | 0.006 | 2.43 (1.16–5.10) | 0.019 |
| ≥3 | 3.80 (1.42–10.15) | 0.008 | 1.39 (0.38–5.09) | 0.623 |
| Nodal status | ||||
| 0 | Reference | Reference | Reference | Reference |
| 1 | 1.62 (1.03–2.55) | 0.037 | 1.45 (0.90–2.34) | 0.128 |
| 2 | 2.55 (1.35–4.84) | 0.004 | 3.14 (1.24–7.99) | 0.016 |
HR, hazard ratio; CI, confidence interval; AURK, Aurora kinase.