Figure 2a:

Biodistribution of ⁶⁴Cu-DOTA-ECL1i in mice with lung injury. Mice were not treated (naive) or received intratracheal PBS or LPS. (a) Photomicrographs (original magnification, ×400) illustrate immunostaining for CCR2 24 hours after intratracheal delivery of PBS or LPS. Tissues were counterstained with hematoxylin. Bar = 50 μm. (b) Chart shows biodistribution of ⁶⁴Cu-DOTA-ECL1i at 24 hours in treatment-naive, PBS, and LPS groups. Data are means ± standard deviations. There were four mice per group. * = P < .001 (two-way analysis of variance with Tukey test).