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. 2017 Apr 25;13(6):4748–4754. doi: 10.3892/ol.2017.6091

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Effect of PE and CDDP alone and in combination on (A) tumor volume, (B) tumor weight and (C) tumor weight inhibitory ratio in subcutaneously CaSki cervical cancer xenografts of nude mice. Eight mice were used in each group. (A and B) The tumor burden was reduced significantly in the CDDP group, but not in the PE group. However, when PE was combined with CDDP, either tumor volume or tumor weight had a remarkable reduction compared with that displayed by the CDDP group (P<0.05 and P<0.01, respectively). (C) The tumor weight inhibitory ratio of the combined group was larger than that of the CDDP (P<0.05) or the control (P<0.01) groups. (D) Images of the tumors from the subcutaneous nude-mouse model for the different groups. PE, Pinelliapedatisecta; CDDP, cis-dichlorodiammineplatinum-II; SD, standard deviation.