Table I.
Comparative analysis of clinical and histopathological characteristics between EBV(+) and EBV(−) GC.
| Case | Sex | Age | T | ly | v | N | M | Stage | Histo-pathological classification | Location | State | Survival time, days | EBER1 | EBV-LMP-1 | AID H-score | NF-κB H-score | PAX5 H-score | c-Myb H-score | Mean USSa (Helico-bacter pylori) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EBV(+) GC | |||||||||||||||||||
| 1 | Male | 48 | 1b | 1 | 0 | 0 | 0 | IA | GCLS | UT | NED | 3,469 | + | − | 20 | 190 | 0 | 70 | 1.6 (−) |
| 2 | Male | 68 | 3 | 1 | 1 | 0 | 0 | IIA | GCLS | UT | NED | 1,350 | + | − | 100 | 19 | 0 | 80 | 1.8 (+) |
| 3 | Male | 52 | 2 | 1 | 3 | 0 | 0 | IB | GCLS | MT | NED | 1,525 | + | − | 70 | 70 | 0 | 10 | 2.2 (+) |
| 4 | Male | 53 | 3 | 1 | 3 | 1 | 0 | IIB | GCLS | MT | NED | 1,839 | + | − | 3 | 15 | 65 | 190 | 2.2 (+) |
| 5 | Male | 74 | 1b | 1 | 0 | 1 | 0 | IB | GCLS | UT | NED | 1,512 | + | − | 5 | 15 | 0 | 40 | 1.8 (+) |
| 6 | Male | 63 | 1b | 0 | 0 | 0 | 0 | IA | GCLS | UT | NED | 845 | + | − | 80 | 80 | 0 | 70 | 2.4 (+) |
| 7 | Male | 77 | 1b | 0 | 0 | 0 | 0 | IA | GCLS | MT | NED | 700 | + | − | 90 | 90 | 35 | 225 | 2.0 (−) |
| 8 | Male | 54 | 1b | 2 | 1 | 0 | 0 | IA | GCLS | MT | NED | 675 | + | − | 30 | 75 | 60 | 110 | 1.4 (+) |
| 9 | Male | 45 | 1b | 0 | 0 | 0 | 0 | IA | GCLS | UT | NED | 657 | + | − | 90 | 85 | 0 | 160 | 1.4 (+) |
| 10 | Male | 60 | 1b | 0 | 0 | 0 | 0 | IA | GCLS | MT | NED | 391 | + | − | 30 | 24 | 0 | 60 | 0.2 (−) |
| 11 | Male | 58 | 3 | 2 | 2 | 2 | 0 | IIIA | por2>tub2 | LT | NED | 706 | + | − | 53 | 120 | 110 | 220 | 1.4 (−) |
| EBV(−) GC | |||||||||||||||||||
| 12 | Male | 77 | 2 | 1 | 1 | 0 | 0 | IB | GCLS | LT | NED | 1,115 | − | − | 60 | 8 | 140 | 70 | 1.8 (−) |
| 13 | Male | 73 | 3 | 2 | 3 | 2 | 0 | IIIA | GCLS | R | STD | 2,250 | − | − | 170 | 10 | 60 | 210 | 1.6 (−) |
| 14 | Male | 73 | 1b | 0 | 0 | 0 | 0 | IA | GCLS | MT | NED | 773 | − | − | 120 | 50 | 0 | 260 | 2.0 (+) |
| 15 | Female | 68 | 2 | 1 | 2 | 0 | 0 | IB | GCLS | LT/MT | NED | 2,161 | − | − | 10 | 55 | 105 | 125 | 2.0 (+) |
| 16 | Male | 76 | 1b | 1 | 0 | 0 | 0 | IA | GCLS | R | NED | 2,943 | − | − | 110 | 17 | 0 | 90 | 2.0 (+) |
| 17 | Male | 77 | 1b | 2 | 2 | 0 | 0 | IA | tub2>tub1 | MT | SAC | 127 | − | − | 9 | 140 | 150 | 40 | 2.0 (+) |
| 18 | Male | 71 | 2 | 1 | 1 | 0 | 0 | IB | sig>por2 | MT | NED | 2,876 | − | − | 3 | 140 | 0 | 20 | 2.0 (+) |
| 19 | Male | 69 | 2 | 2 | 1 | 0 | 0 | IB | tub1> tub2>muc | UT | NED | 187 | − | − | 135 | 240 | 100 | 16 | 2.4 (+) |
| 20 | Male | 66 | 1b | 1 | 1 | 0 | 0 | IA | tub>por2 | MT | NED | 2,610 | − | − | 30 | 295 | 120 | 80 | 1.6 (+) |
| 21 | Female | 58 | 1b | 2 | 2 | 0 | 0 | IA | tub2 | MT | NED | 2,511 | − | − | 70 | 280 | 120 | 95 | 2.2 (+) |
| 22 | Male | 57 | 2 | 1 | 1 | 0 | 0 | IB | sig | MT | NED | 2,530 | − | − | 150 | 110 | 0 | 60 | 1.2 (+) |
| 23 | Male | 49 | 1b | 1 | 1 | 0 | 0 | IA | por2>tub2 | UT | NED | 1,078 | − | − | 45 | 295 | 100 | 95 | 2.4 (+) |
| 24 | Male | 59 | 1b | 1 | 0 | 0 | 0 | IA | tub1>tub2 | MT | NED | 2,493 | − | − | 30 | 255 | 70 | 24 | 2.2 (+) |
| 25 | Male | 67 | 1b | 1 | 0 | 0 | 0 | IA | por2>sig | MT | NED | 2,435 | − | − | 105 | 140 | 10 | 75 | 1.8 (+) |
| 26 | Male | 69 | 1b | 1 | 1 | 0 | 0 | IA | tub1>tub2 | UT | NED | 2,211 | − | − | 90 | 230 | 100 | 180 | 2.0 (+) |
| 27 | Male | 77 | 1b | 1 | 3 | 0 | 0 | IA | tub2 | R | NED | 1,634 | − | − | 80 | 125 | 90 | 170 | 0.8 (−) |
| 28 | Male | 70 | 1b | 2 | 2 | 1 | 0 | IB | tub2 | UT | SAC | 403 | − | − | 70 | 180 | 60 | 170 | 1.8 (+) |
| 29 | Male | 63 | 3 | 1 | 1 | 0 | 0 | IIA | tub1 | MT | NED | 1,520 | − | − | 35 | 150 | 100 | 75 | 1.8 (+) |
| 30 | Male | 70 | 3 | 2 | 3 | 1 | 0 | IIB | tub2 | MT | NED | 898 | − | − | 145 | 40 | 0 | 5 | 2.2 (+) |