Table II.

Association between expression of AID and AID-regulatory factors and clinicopathological parameters in gastric cancers (n=30) regardless of EBV infection.

Factor	AID (+)	P-value	NF-κB (+) (AID activator)	P-value	PAX-5 (+) (AID activator)	P-value	c-Myb (+) (AID silencer)	P-value
T		0.572		0.215		0.831		0.465
1b (n=18)	3		10		7		7
2 (n=6)	2		2		3		1
3 (n=6)	2		1		2		3
ly		0.539		0.100		0.134		0.218
0 (n=5)	1		0		0		3
1 (n=17)	3		9		8		4
2 (n=8)	3		4		4		4
v		0.456		0.317		0.022a		0.292
0 (n=10)	3		3		1		3
1 (n=10)	2		6		6		2
2 (n=5)	0		3		4		3
3 (n=5)	2		1		1		3
N		0.642		0.285		0.213		0.114
0 (n=24)	5		12		11		7
1 (n=4)	1		1		0		2
2 (n=2)	1		0		1		2
Stage		0.663		0.368		0.806		0.264
IA (n=16)	3		9		7		6
IB (n=8)	2		3		3		2
IIA (n=2)	0		1		1		0
IIB (n=2)	1		0		0		1
IIIA (n=2)	1		0		1		2
Location		0.179		0.387		0.172		0.389
Upper third (n=9)	1		5		3		3
Middle third (n=15)	4		7		5		4
Lower third (n=3)	0		0		3		2
Remnant GC (n=3)	2		1		1		2
Age, years		0.089		0.462		0.590		0.421
<65 (n=13)	1		5		5		4
≥65 (n=17)	6		8		7		7
Mean USS		0.623		0.515		0.073		0.310
≥2.2 (n=22)	5		9		11		7
<2.2 (n=8)	2		4		1		4

AID, activation-induced cytidine deaminase; NF-κB, nuclear factor κB; PAX5, paired box 5; c-Myb, c-Myb proto-oncogene; T, tumor; ly, lymphatic; v, venous; N, node; GC, gastric carcinoma; USS, updated Sydney system.

^aStatistically significant.