SIRP-α is decreased in CaP cells and tissues. (A) Reverse transcription-qPCR analysis of SIRP-α expression in CaP and adjacent normal tissues. (B) Western blotting for SIRP-α in paired normal and tumor tissues. (C) qPCR and (D) western blotting results comparing SIRP-α levels between ADPC and AIPC tissues. (E) mRNA and (F) protein expression levels of SIRP-α in the prostate RWPE-1, PWR1-E, LNCAP, LNCAP-A and PC-3 cell lines. SIRP, signal regulatory protein; CaP, prostate cancer; qPCR, quantitative polymerase chain reaction; ADPC, androgen-dependent prostate cancer; AIPC, androgen-independent prostate cancer.