Table 2. Median relative abundance in EnzD and Non-EnzD groups; estimated change (EnzD- Non-EnzD); in Median RA by Genera.

Genera	EnzD%	Non-EnzD%	Estimated change in RA%	P-value	Corrected p-value
OP
Streptococcus	36.51	14.81	21.75	<0.01	<0.01
Prevotella	6.62	16.20	−10.90	<0.01	<0.01
Veillonella	9.27	19.22	−7.86	<0.01	<0.01
Neisseria	0.72	1.94	−3.62	<0.01	<0.01
Actinomyces	2.93	0.73	2.50	<0.01	<0.01
Granulicatella	1.80	2.44	−0.62	<0.01	<0.01
Gemella	1.89	0.64	1.23	<0.01	<0.01
Leptotrichia	1.16	3.79	−1.44	<0.01	<0.01
Fusobacterium	1.47	3.08	−0.56	<0.01	<0.01
Rothia	1.70	0.27	1.25	<0.01	<0.01
Haemophilus	0.45	1.69	−0.91	<0.01	<0.01
Johnsonella	0.97	0.40	1.19	<0.01	<0.01
Campylobacter	0.50	0.75	−0.25	<0.01	<0.01
Sputum
Streptococcus	27.85	22.48	1.33	0.50	0.50
Staphylococcus	1.39	0.62	5.47	<0.01	<0.01
Prevotella	0.88	3.54	−1.91	<0.01	<0.01
Veillonella	1.09	6.01	−3.55	<0.01	<0.01
Granulicatella	0.53	1.77	−1.30	<0.01	<0.01
Gemella	0.53	1.68	−0.62	<0.01	0.02
Rothia	0.84	0.57	0.21	0.24	0.27