Table 3. Displays the RA for CF pathogens detected in each sample.
Samples are highlighted when the difference in relative abundance was at least 1%, red for increase with EnzD and blue with a decrease. The grey rows indicate the median (min, max) for the difference in relative abundance for the highlighted samples.
| Staphylococcus | Achromobacter | Haemophilus | Stenotrophomonas | Pseudomonas | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Non EnzD | EnzD | Non EnzD | EnzD | Non EnzD | EnzD | Non EnzD | EnzD | Non EnzD | EnzD | |
| OP | ||||||||||
| OP1 | 0 | 0.01% | 0 | 0 | 1.63% | 0.34% | 0 | 0 | 0 | 0 |
| OP2 | 0 | 0.08% | 0 | 0 | 4.03% | 1.56% | 0 | 0 | 0 | 0 |
| OP3 | 0.01% | 0.07% | 0 | 0 | 0.04% | 0 | 0 | 0 | 0 | 0 |
| OP4 | 0.01% | 0.03% | 0 | 0 | 1.96% | 0.56% | 0 | 0 | 0 | 0 |
| OP5 | 0.01% | 0.04% | 0 | 0 | 2.65% | 0.83% | 0 | 0 | 0 | 0 |
| OP6 | 0 | 0.01% | 0 | 0 | 0.00% | 0.01% | 0 | 0.01% | 0 | 0 |
| OP7 | 0 | 0 | 0 | 0 | 5.71% | 1.46% | 0 | 0 | 0 | 0 |
| OP8 | 0.15% | 1.13% | 0 | 0 | 2.05% | 0.65% | 0 | 0 | 0 | 0 |
| OP9 | 0 | 0.02% | 0 | 0 | 15.12% | 7.11% | 0 | 0 | 0 | 0 |
| OP10 | 0 | 0.04% | 0 | 0 | 0.25% | 0.08% | 0 | 0 | 0 | 0 |
| OP11 | 0.01% | 0.03% | 0 | 0 | 5.86% | 2.03% | 0 | 0 | 0 | 0 |
| OP12 | 0.02% | 0.03% | 0 | 0 | 0.21% | 0.11% | 0 | 0 | 0.01% | 0.02% |
| OP13 | 0.08% | 0.30% | 0 | 0 | 1.19% | 0.22% | 0.01% | 0 | 0 | 0 |
| OP14 | 0.06% | 0.37% | 0 | 0 | 2.41% | 1.43% | 0 | 0 | 0.03% | 0 |
| OP15 | 0.07% | 1.02% | 0 | 0 | 0.03% | 0.04% | 0 | 0 | 0.01% | 0.01% |
| OP16 | 0.04% | 0.05% | 0 | 0 | 0.09% | 0.02% | 0 | 0 | 0 | 0 |
| OP17 | 0.01% | 0.08% | 0 | 0 | 0.57% | 0.31% | 0 | 0 | 0 | 0 |
| OP18 | 0.01% | 0.01% | 0 | 0 | 3.49% | 1.87% | 0 | 0 | 0.01% | 0.01% |
| OP19 | 0.01% | 0.57% | 0 | 0 | 1.91% | 0.57% | 0 | 0 | 0 | 0.01% |
| OP20 | 0 | 0 | 0 | 0 | 3.45% | 1.79% | 0 | 0 | 0 | 0 |
| OP21 | 0.02% | 0.10% | 0 | 0 | 0.40% | 0.18% | 0 | 0 | 0.01% | 0.02% |
| OP22 | 0 | 0 | 0 | 0 | 0.35% | 0.05% | 0 | 0 | 0.01% | 0.05% |
| OP23 | 0.07% | 0.18% | 0 | 0 | 11.95% | 7.84% | 0.01% | 0 | 0 | 0.01% |
| OP24 | 0 | 0 | 0 | 0 | 0.17% | 0.03% | 0 | 0 | 0 | 0 |
| OP25 | 0.01% | 0.01% | 0 | 0 | 0.23% | 0.07% | 0.01% | 0.01% | 0.02% | 0.01% |
| OP26 | 2.17% | 3.92% | 0 | 0 | 0.45% | 0.04% | 0 | 0 | 0.01% | 0 |
| OP27 | 0.11% | 0.16% | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.01% |
| OP28 | 0.05% | 0 | 0 | 0 | 2.44% | 1.82% | 0 | 0 | 0 | 0 |
| OP29 | 0 | 0 | 0 | 0 | 1.75% | 0.67% | 0.05% | 0.03% | 0 | 0 |
| OP30 | 0.01% | 0.03% | 0 | 0 | 40.38% | 30.81% | 0 | 0 | 0 | 0 |
| OP31 | 0 | 0 | 0 | 0 | 0.61% | 0.14% | 0 | 0 | 0 | 0 |
| OP32 | 0.01% | 0.01% | 0 | 0 | 3.40% | 1.09% | 0 | 0 | 0.07% | 0.06% |
| OP33 | 0 | 0 | 0 | 0 | 0.30% | 0.04% | 0 | 0 | 0 | 0 |
| OP34 | 3.34% | 14.25% | 0 | 0 | 2.01% | 1.19% | 0 | 0 | 0 | 0 |
| OP35 | 0.05% | 0.08% | 0 | 0 | 4.44% | 4.27% | 0 | 0 | 0 | 0 |
| OP36 | 0.02% | 0.22% | 0 | 0 | 0.03% | 0.01% | 0 | 0 | 0 | 0 |
| OP37 | 0.11% | 0.19% | 0 | 0 | 2.06% | 0.58% | 0 | 0 | 0 | 0 |
| OP38 | 0.01% | 0.04% | 0 | 0 | 3.68% | 1.54% | 0 | 0 | 0 | 0 |
| OP39 | 0.06% | 0.07% | 0 | 0 | 0 | 0 | 0 | 0 | 0.01% | 0 |
| OP40 | 0.13% | 0.11% | 0 | 0 | 0.01% | 0 | 0 | 0 | 0.01% | 0.02% |
| OP41 | 0.05% | 0.03% | 0 | 0 | 1.91% | 1.20% | 0 | 0 | 0 | 0 |
| OP42 | 0.01% | 0.01% | 0 | 0 | 0.05% | 0.01% | 0 | 0 | 0.02% | 0.01% |
| 6.3 (1.8, 10.9) | – | −1.8 (−1.1, −9.6) | – | – | ||||||
| Sputum | ||||||||||
| ES1 | 2.24% | 1.99% | 0 | 0 | 0 | 0 | 0 | 0 | 0.66% | 0.51% |
| ES2 | 0.01% | 0.05% | 0 | 0 | 2.89% | 2.79% | 0 | 0 | 39.12% | 79.91% |
| ES3 | 0 | 0 | 0 | 0 | 8.77% | 0.83% | 0 | 0 | 0 | 0.01% |
| ES4 | 0.05% | 0.12% | 0 | 0 | 9.52% | 6.47% | 0 | 0 | 1.27% | 1.02% |
| ES5 | 34.61% | 72.13% | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.01% |
| ES6 | 43.91% | 84.67% | 0 | 0 | 0.01% | 0 | 0 | 0 | 5.04% | 1.39% |
| ES7 | 89.38% | 97.47% | 0 | 0 | 0 | 0 | 0.07% | 0.02% | 0.01% | 0 |
| ES8 | 16.72% | 32.21% | 0 | 0 | 0 | 0 | 0 | 0 | 52.01% | 9.96% |
| ES9 | 0.49% | 8.24% | 0 | 0 | 1.53% | 0.71% | 0 | 0 | 26.46% | 33.92% |
| ES10 | 0.20% | 0.35% | 0 | 0 | 0.54% | 0.09% | 0 | 0 | 0 | 0.01% |
| ES11 | 31.47% | 96.31% | 0 | 0 | 4.11% | 0.23% | 0.14% | 0.02% | 0.01% | 0 |
| ES12 | 0.04% | 0.04% | 0 | 0 | 0 | 0 | 0 | 0 | 10.08% | 3.89% |
| ES13 | 26.05% | 11.45% | 0 | 0 | 1.08% | 0.72% | 0 | 0 | 31.81% | 58.28% |
| ES14 | 0.06% | 0.13% | 0 | 0 | 0 | 0 | 0 | 0 | 0.02% | 0.03% |
| ES15 | 16.08% | 29.44% | 0 | 0 | 11.39% | 7.50% | 0 | 0 | 13.04% | 14.15% |
| ES16 | 1.48% | 7.26% | 0 | 0 | 2.26% | 1.25% | 0 | 0 | 52.82% | 63.76% |
| ES17 | 67.38% | 86.70% | 0 | 0 | 0.17% | 0.02% | 0 | 0 | 1.69% | 0.88% |
| ES18 | 0.03% | 0.05% | 0 | 0 | 0 | 0 | 0 | 0 | 0.01% | 0.03% |
| ES19 | 0.62% | 1.39% | 0 | 0 | 6.75% | 2.09% | 11.95% | 12.85% | 0.01% | 0 |
| ES20 | 88.34% | 98.55% | 0 | 0 | 0 | 0 | 0 | 0 | 0.01% | 0 |
| ES21 | 0.01% | 0.01% | 0 | 0 | 0 | 0 | 56.44% | 37.37% | 0 | 0 |
| ES22 | 1.08% | 1.31% | 0 | 0 | 6.74% | 8.94% | 0 | 0 | 0 | 0 |
| ES23 | 0.07% | 0.34% | 0 | 0 | 0.01% | 0 | 0 | 0 | 0.16% | 0.23% |
| ES24 | 0.07% | 0.15% | 0 | 0 | 0.60% | 0.28% | 0.01% | 0 | 87.24% | 81.12% |
| ES25 | 0 | 0 | 0 | 0 | 1.18% | 0.41% | 2.41% | 1.51% | 0 | 0 |
| ES26 | 41.52% | 87.96% | 0 | 0 | 5.60% | 0.64% | 0 | 0 | 0 | 0 |
| ES27 | 64.41% | 97.56% | 0 | 0 | 0.43% | 0.02% | 2.93% | 0.11% | 0 | 0 |
| ES28 | 0.02% | 0.04% | 0 | 0 | 0.01% | 0 | 0.01% | 0.04% | 0.02% | 0.01% |
| ES29 | 73.98% | 98.00% | 0.01% | 0 | 0 | 0 | 0 | 0 | 0.05% | 0.01% |
| ES30 | 72.00% | 87.13% | 0 | 0 | 0 | 0 | 0 | 0 | 0.18% | 0.14% |
| ES31 | 90.32% | 96.74% | 0 | 0 | 0 | 0 | 0.01% | 0.01% | 0 | 0 |
| ES32 | 0.02% | 0.01% | 0 | 0 | 0.02% | 0 | 33.62% | 57.14% | 0.07% | 0.04% |
| ES33 | 49.36% | 78.78% | 0 | 0 | 0 | 0 | 0.07% | 0 | 0.03% | 0.06% |
| ES34 | 0.05% | 0.15% | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.03% |
| ES35 | 1.84% | 7.29% | 0 | 0 | 0.66% | 0.40% | 0.17% | 0.10% | 22.94% | 21.79% |
| ES36 | 0.30% | 0.16% | 0 | 0 | 0.32% | 0.02% | 0.01% | 0.02% | 28.07% | 96.42% |
| ES37 | 0 | 0.02% | 0 | 0 | 1.90% | 1.22% | 0 | 0 | 0.18% | 0.31% |
| ES38 | 0.16% | 0.53% | 0.08% | 0.10% | 0.05% | 0.10% | 0 | 0 | 0.01% | 0.03% |
| ES39 | 0.01% | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.01% |
| 15.3 (−14.6, 64.8) | – | −3.9 (−7.9, 2.2) | −2.8 (−19.1, 23.5) | 1.1 (−42.0, 68.4) | ||||||