Figure 2.

Overexpression of Bmi-1 and PADI4 in esophageal squamous cell carcinoma tumors. A total of 8 paired primary esophageal tumors and normal esophageal tissue from the same patient were determined for (A) Bmi-1 and (B) PADI4 expression at the protein level by western blot analysis. The expression level was normalized to GAPDH. (C) The expression levels of Bmi-1 and PADI4 were significantly increased in ESCC compared with para-carcinoma tissue samples. Bmi-1, B-cell specific Moloney leukemia virus insert site 1; PADI4, peptidyl arginine deiminase IV; T, primary esophageal tumors; N, normal esophageal tissue.