Skip to main content
. 2017 May 30;5:e3357. doi: 10.7717/peerj.3357

Table 2. Inhibition of tubulin polymerization in vitro.

Compounds IC50
Colchicinea 2.86 ± 0.16μM
Vinblastinea 1.57 ± 0.34μM
Latrunculin Bb >1 mM
Cucurbitacin B >1 mM
Cucurbitacin E 566.91 ± 113.5μM
Cucurbitacin I >1 mM

Notes.

a

Active on tubulin/microtubules.

b

Active against actin filaments; data are presented as mean ± SD.