Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 13;13(6):5009–5015. doi: 10.3892/ol.2017.6033

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, Spandidos Publications

PMC Copyright notice

Figure 3. — IGF-1R is a direct target of miR-10b in cervical cancer. (A) Predicted miR-10b target sequence in the 3′UTR of IGF-1R and positions of mutated nucleotides in the 3′UTR of IGF-1R. (B) HEK293T cells were transfected with luciferase report vectors, together with miR-10b mimics or NC. Luciferase activities were measured at 48 h post-transfection. (C) The protein expression levels of IGF-1R were determined by western blot analysis. *P<0.05. IGF-1R, insulin-like growth factor-1 receptor; miR-10b, microRNA-10b; UTR, untranslated region; Wt, wild type; mut, mutant; NC, negative control.

Figure 3. — IGF-1R is a direct target of miR-10b in cervical cancer. (A) Predicted miR-10b target sequence in the 3′UTR of IGF-1R and positions of mutated nucleotides in the 3′UTR of IGF-1R. (B) HEK293T cells were transfected with luciferase report vectors, together with miR-10b mimics or NC. Luciferase activities were measured at 48 h post-transfection. (C) The protein expression levels of IGF-1R were determined by western blot analysis. *P<0.05. IGF-1R, insulin-like growth factor-1 receptor; miR-10b, microRNA-10b; UTR, untranslated region; Wt, wild type; mut, mutant; NC, negative control.