Table 1. Table of clinicopathological features in different HPV status.
Correlation between the clinicopathological features and HPV status.
| Variables | No. | HPV (−) | HPV (+) | p value |
|---|---|---|---|---|
| Gender | ||||
| Male | 103 | 89 | 14 | 1.000 |
| Female | 3 | 3 | 0 | |
| Age | ||||
| <60 y/o | 52 | 49 | 3 | 0.042* |
| ≥60 y/o | 54 | 43 | 11 | |
| T classification | ||||
| T1 and T2 | 74 | 64 | 10 | 1.000 |
| T3 and T4a | 32 | 28 | 4 | |
| N classification | ||||
| Positive | 28 | 25 | 3 | 0.756 |
| Negative | 78 | 67 | 11 | |
| TNM stage | ||||
| Stage I and II | 62 | 54 | 8 | 1.000 |
| Stage III and IV | 44 | 38 | 6 | |
| Extranodal extension | ||||
| Positive | 16 | 15 | 1 | 0.560 |
| Negative | 12 | 10 | 2 | |
| Adjuvant RT/CCRT | ||||
| Yes | 27 | 24 | 3 | 1.000 |
| No | 79 | 68 | 11 | |
| Tumor recurrence | ||||
| Yes | 23 | 23 | 0 | 0.037* |
| No | 83 | 69 | 14 | |
| Second primary cancer | ||||
| Yes | 18 | 15 | 3 | 0.703 |
| No | 88 | 77 | 11 | |
| Tumor differentiation | ||||
| Well | 28 | 25 | 3 | 0.756 |
| Moderate and poor | 78 | 67 | 11 | |
| Tumor subsites | ||||
| Transglottic | 11 | 11 | 0 | 0.117 |
| Glottic | 54 | 47 | 7 | |
| Supraglottic | 40 | 34 | 6 | |
| Subglottic | 1 | 0 | 1 | |
| Tobacco use | ||||
| Smoking | 93 | 83 | 10 | 0.068** |
| Non-smoking | 13 | 9 | 4 | |
| Alcohol use | ||||
| Drinking | 51 | 47 | 4 | 0.154 |
| Non-drinking | 55 | 45 | 10 | |
| Betel nut chewing | ||||
| Chewing | 53 | 46 | 7 | 1.000 |
| Non-chewing | 53 | 46 | 7 |
Notes.
- RT
- radiotherapy
- CCRT
- concurrent chemoradiotherapy
*
Statistical significance.
**
Marginal significance.