. 2017 May 30;5:e3395. doi: 10.7717/peerj.3395

Table 2. Table of outcome according to different clinicopathological features.

Actuarial 5-year overall survival, disease-specific survival and local/regional control rate according to the clinicopathological features.

Variable	No	OS	p-value	DSS	p-value	Recurrence- free	p-value
HPV status
Positive	14	64.3	0.8056	100	0.1485	100	0.0494^*
Negative	92	67.4		84.8		75.0
Gender
Male	103	67.0	0.9186	87.4	0.3010	79.6	0.0490^*
Female	3	66.7		66.7		33.3
Age
<60 y/o	52	76.9	0.0416^*	86.5	0.9345	78.9	0.8140
≥60 y/o	54	57.4		87.0		77.8
Tumor differentiation
Well	28	78.6	0.1416	96.4	0.0818	78.6	0.9210
Moderate/poor	78	62.8		83.3		78.2
Tumor site
Glottic	54	81.5	0.0011^*	96.3	0.0021^*	81.5	0.2499
Non-Glottic	52	51.9		76.9		75.0
ENE
Yes	16	37.5	0.1563	56.3	0.1177	68.8	0.1230
No	12	66.7		83.3		91.7
T classification
T1 and T2	74	70.3	0.1762	90.5	0.0589^**	79.7	0.4137
T3 and T4a	32	59.4		78.1		75.0
N classification
Negative	78	73.1	0.0161^*	93.6	0.0003^*	78.2	0.9535
Positive	28	50.0		67.9		78.6
TNM stage
I, II	62	72.6	0.1044	95.2	0.0021^*	80.7	0.3744
III, IVa	44	59.1		75.0		75.0
Second primary cancer
Yes	18	44.4	0.0338^*	100	0.1059	88.9	0.3066
No	88	71.6		84.1		76.1
Adjuvant RT/CCRT
Yes	27	63.0	0.5087	81.5		88.9	0.1271
No	79	68.4		88.6	0.3121	74.7

Notes.

Statistical significance.

^**

Marginal significance.