Table I.
General characteristics of the Philadelphia-negative myeloproliferative neoplasm cases (n=133) and control population (n=281).
| Characteristics | Cases, n (%) | Controls, n (%) | P-valuec |
|---|---|---|---|
| Gender | 0.780 | ||
| Male | 61 (45.9) | 133 (47.3) | |
| Female | 72 (54.1) | 148 (52.7) | |
| Age, yearsa,b | 0.622 | ||
| 30–49 | 16 (12.0) | 43 (15.3) | |
| 50–69 | 50 (37.6) | 107 (38.1) | |
| ≥70 | 67 (50.4) | 131 (46.6) | |
| Tobacco smoking habits | 0.633 | ||
| Never | 104 (78.2) | 213 (76.1) | |
| Current | 29 (21.8) | 67 (23.9) | |
| Alcohol consumption habits | <0.0001 | ||
| Never | 103 (77.4) | 191 (68.2) | |
| Social | 20 (15.0) | 25 (8.9) | |
| Regular | 10 (7.5) | 64 (22.9) | |
| JAK2 V617F mutation | 0.020 | ||
| Yes | 99 (75.0) | ||
| ET | 58 (73.4) | ||
| PV | 34 (87.2) | ||
| PMF | 7 (50.0) | ||
| No | 33 (25.0) |
a
Age at diagnosis for cases.
b
Age of control population at the time of diagnosis for the matched case.
c
P-value determined by χ2 test. ET, essential thrombocythaemia; PV, polycythaemia vera; PMF, primary myelofibrosis.