Table I.

Results of the mouse orthotopic model of bladder cancer using UMUC-3 cells.

Characteristics	Control	Periostin	P-value
n	7	9
Body weight, ga	23.8±1.6	24.4±1.0	0.335
Bladder weight, mga	61.7±20.0	39.4±11.0	0.013
Tumor formationb	6/7 (85.7%)	5/9 (55.6%)	0.455
Bladder weight of tumor formed mouse, mga	66.7±16.3	46.6±9.7	0.039
Muscle invasion of bladder tumorb	5/6 (83.3%)	0/5 (0%)	0.031
Mitotic activity indexa	12.0±3.0	11.9±3.5	0.974

^aMean ± standard deviation

^bn (%).