Table II.
Ocoxin Oral solution® (O), irinotecan (I) and the combined therapy (OI) deregulated genes.a
| Gene symbol | O vs. C | OI vs. C | I vs. C |
|---|---|---|---|
| 1700017G19Rik | ↓↓ | ||
| 1700086P04Rik | ↓ | ||
| 2700081O15Rik | ↑ | ||
| 2810454H06Rik | ↓↓↓ | ||
| 4930401B11Rik | ↓ | ||
| 4930556N13Rik | ↓↓ | ||
| 4933413J09Rik | ↓↓ | ||
| 4933415F23Rik | ↓ | ||
| 6430550D23Rik | ↓↓ | ||
| 9530003O04Rik | ↓ | ||
| A730028G07Rik | ↓↓↓ | ||
| Aak1 | ↓ | ||
| Adcy6 | ↓↓ | ||
| Afm | ↓↓↓ | ||
| Agxt2 | ↓↓ | ||
| AI481877 | ↓↓ | ||
| Ankk1 | ↑↑ | ||
| Apoe | ↓ | ||
| Aqp9 | ↓↓ | ||
| Arglu1 | ↓ | ↓ | ↓ |
| Atf6 | ↓↓↓ | ||
| B230334C09Rik | ↑↑ | ||
| BC030308 | ↑ | ||
| Bfar | ↓ | ||
| Bmp7 | ↑↑ | ||
| Bsph1 | ↓↓ | ||
| C030039L03Rik | ↓↓ | ||
| Cabp1 | ↑↑ | ||
| Cdh9 | ↑ | ||
| Cdk13 | ↑↑↑↑ | ||
| Cela3a | ↓↓↓ | ||
| Cfap61 | ↓ | ||
| Cfd | ↑↑ | ||
| Chil3 | ↑↑↑ | ||
| Cic | ↓↓ | ||
| Clcn7 | ↓↓ | ||
| Clec18a | ↓↓ | ||
| Clec2e | ↓ | ||
| Crygc | ↓↓ | ||
| Cyp19a1 | ↓ | ||
| Cypt15 | ↑↑↑ | ||
| Cypt2 | ↓ | ||
| Cyth4 | ↑↑↑↑ | ||
| D430018E03Rik | ↓↓ | ||
| D6Ertd527e | ↓↓ | ||
| Dlx6os1 | ↓ | ||
| Dnal1 | ↓ | ||
| Dock4 | ↓↓ | ||
| Dsc1 | ↓ | ||
| Dzip1 | ↑ | ||
| Ect2 | ↑↑↑ | ||
| Erich2 | ↓↓ | ||
| Fam71f2 | ↑↑↑ | ||
| Fanci | ↓ | ||
| Fat3 | ↓↓ | ||
| Fgr | ↓↓ | ||
| Fkbp6 | ↓ | ||
| Fuca2 | ↓↓ | ||
| Gja8 | ↓↓ | ||
| Glrx2 | ↓↓ | ||
| Gm10760 | ↓ | ||
| Gm16794 | ↓↓ | ||
| Gm38485 | ↑ | ||
| Gm5126 | ↓↓ | ||
| Gm5129 | ↓↓ | ||
| Gm5941 | ↓↓ | ||
| Gm8075 | ↓↓ | ||
| Gm9548 | ↓↓ | ||
| Gm9798 | ↓↓ | ||
| Gm9979 | ↑ | ||
| Gpr22 | ↓↓ | ||
| Hcrt | ↓↓ | ||
| Hist2h3c2 | ↓↓ | ||
| Hmcn1 | ↑ | ||
| Hras | ↓↓ | ||
| Il11 | ↑↑↑↑ | ||
| Il1b | ↑↑ | ||
| Kcnj12 | ↓ | ||
| Kif14 | ↓↓ | ||
| Klf11 | ↓↓↓ | ||
| Krtap19–2 | ↑↑↑ | ||
| LOC102641211 | ↑ | ||
| LOC105244659 | ↓↓ | ||
| Lppr3 | ↓↓↓ | ||
| Lrrc2 | ↓↓↓ | ||
| Ly6c1 | ↓↓↓ | ||
| Marcksl1 | ↑ | ||
| Marcksl1-ps4 | ↑ | ||
| Marveld2 | ↓↓ | ||
| Meg3 | ↓ | ||
| Ms4a1 | ↓↓ | ||
| Naprt | ↓ | ||
| Ncam1 | ↓↓ | ||
| Nctc1 | ↑↑ | ||
| Nfkbid | ↓↓ | ||
| Nkx6-1 | ↓↓ | ||
| Nol3 | ↑↑ | ||
| Nr1h3 | ↓ | ||
| Ntrk1 | ↑ | ||
| Nuf2 | ↑↑↑↑ | ||
| Olfr1110 | ↓↓↓ | ||
| Olfr328 | ↓↓↓ | ||
| Olfr549 | ↓↓ | ||
| Olfr945 | ↓↓ | ||
| Olfr97 | ↓↓ | ||
| Pggt1b | ↑↑↑ | ||
| Phka2 | ↓↓ | ||
| Pir | ↑ | ||
| Pyroxd2 | ↑↑ | ||
| Raver2 | ↓↓ | ||
| Recql5 | ↓ | ||
| Rgs16 | ↑↑ | ||
| Rian | ↓↓ | ||
| Rnf170 | ↓ | ||
| Rnf220 | ↓↓ | ||
| Sclt1 | ↓ | ||
| Scn10a | ↓↓ | ||
| Sel1l | ↓↓ | ||
| Sept8 | ↓↓↓ | ||
| Sf3a2 | ↓↓ | ||
| Sgk3 | ↓↓ | ||
| Shc3 | ↑ | ||
| Slc14a1 | ↑↑ | ||
| Slc1a2 | ↓ | ||
| Slc26a1 | ↓↓ | ||
| Slc5a9 | ↓↓ | ||
| Slc8b1 | ↓↓ | ||
| Snx14 | ↑↑ | ||
| Spice1 | ↓↓ | ||
| Ssh1 | ↑↑ | ||
| Stt3a | ↓↓ | ||
| Sucla2 | ↓↓ | ↓↓ | |
| Tanc1 | ↓↓ | ||
| Tmem29 | ↓↓ | ||
| Tmprss5 | ↓↓ | ||
| Tshz2 | ↓↓ | ||
| Tstd3 | ↑↑↑↑ | ||
| Ttbk1 | ↓ | ||
| Ttl | ↑↑ | ||
| Tuba8 | ↓ | ||
| Ube2cbp | ↓↓ | ||
| Usp2 | ↑↑ | ||
| Usp42 | ↑ | ||
| Vmn1r19 | ↓↓ | ||
| Vps13c | ↓↓ | ||
| Xrcc4 | ↓↓ | ||
| Zdhhc21 | ↓↓↓ | ||
| Zfp318 | ↓↓↓ | ||
| Zpbp2 | ↓↓ | ||
| Zrsr2 | ↑↑ |