Table I.
Relationships between selected clinicopathological factors and distant metastasis.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Clinicopathological factors | No. of cases with metastasis (n=32) | No. of cases without metastasis (n=97) | OR (95% CI) | P-value | OR (95% CI) | P-value |
| Aged (≥70 years old/<70) | 14/18 | 38/59 | 1.21 (0.54–2.54) | 0.68a | ||
| Genderd (male/female) | 18/14 | 54/43 | 1.02 (0.46–2.46) | 1.00a | ||
| Tumor sized (mean ± SD) | 54.1±28.3 | 34.6±18.3 | N/A | <0.001b | 1.03 (1.01–1.01) | 0.007c |
| Tumor locationd (rectum/colon) | 12/20 | 24/73 | 1.83 (0.78–4.78) | 0.18a | ||
| Tumor depthd (T2-T4/T1) | 31/1 | 66/31 | 14.56 (1.90–111.90) | <0.001a | ||
| Lymphatic infiltrationd (+/−) | 25/7 | 54/43 | 2.84 (1.12–7.12) | 0.035a | ||
| Vascular infiltrationd (+/−) | 28/4 | 59/38 | 4.51 (1.46–13.46) | 0.0048a | ||
| Regional lymph node metastasisd (+/−) | 21/11 | 21/76 | 6.91 (2.88–16.88) | <0.001a | 4.76 (1.87–12.87) | 0.001c |
| Por/Muc componentd (+/−) | 9/23 | 22/75 | 1.33 (0.54–3.54) | 0.63a | ||
| Adjuvant chemo therapyd (+/−) | 15/17 | 23/74 | 2.84 (1.23–6.23) | 0.024a | ||
| MVDd (mean ± SD) | 10.4±4.9 | 7.6±3.3 | N/A | 0.0081b | 1.14 (1.02–1.02) | 0.033c |
a
Fisher's exact test
b
Welch's t-test
c
Stepwise multivariate logistic regression
d
Values are expressed as percentage at the 95% confidence interval. No, number; OR, odds ratio; CI, confidence interval; SD, standard deviation; Por, poorly differentiated adenocarcinoma; Muc, mucinous carcinoma; N/A, not applicable; MVD, microvessel density.