E1A-Rb-HDAC model describing the inhibition of E1A-induced cell transformation in the presence of lunasin. Figure previously published in (51). E1A, early region 1A; Rb, retinoblastoma; HDAC, histone deacetylase; DP, dimerization partner; E2F, transcription factor E2F; HAT, histone acetyltransferase.