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. 2017 Apr 25;13(6):4897–4904. doi: 10.3892/ol.2017.6094

Figure 5.

Figure 5.

ELISA analyses show that blueberries reduce the protein levels of COX-2 in SKOV3 cells. SKOV3 cells were transfected with COX-1, COX-2, COX-1 RNAi or COX-2 RNAi, and treated with 0, 2, 4, 8 or 16 mg/ml blueberry juice. The concentrations of COX-2 were measured at days 0, 1, 2 and 3. The data represents the results of 5 independent experiments and are presented as the mean ± standard deviation. P<0.05 compared with 0 µg/ml blueberry subsequent to a 1-, 2- or 3-day culture. COX, cyclooxygenase; RNAi, RNA interference; Control, without transfection or blueberry; 2B, 2 mg blueberry; 4B, 4 mg blueberry; 8B, 8 mg blueberry; 16B, 16 mg blueberry; C1, COX-1; 2BC1, 2 mg blueberry and COX1 transfection; 4BC1, 4 mg blueberry and COX1 transfection; 8BC1, 8 mg blueberry and COX1 transfection; 16BC1, 16 mg blueberry and COX1 transfection; C1i, COX-1 RNAi; 2BC1i, 2 mg blueberry and COX1 RNAi; 4BC1i, 4 mg blueberry and COX1 RNAi; 8BC1i, 8 mg blueberry and COX1 RNAi; 16BC1i, 16 mg blueberry and COX1 RNAi; C2, COX-2; 2BC2, 2 mg blueberry and COX2 transfection; 4BC2, 4 mg blueberry and COX2 transfection; 8BC2, 8 mg blueberry and COX2 transfection; 16BC2, 16 mg blueberry and COX2 transfection; C2i, COX-2 RNAi; 2BC2i, 2 mg blueberry and COX2 RNAi; 4BC2i, 4 mg blueberry and COX2 RNAi; 8BC2i, 8 mg blueberry and COX2 RNAi; 16BC2i, 16 mg blueberry and COX2 RNAi.