Table III.
Top ten enriched functions for the differentially expressed genes.
| ID | Gene ontology term | Count | P-value | Genes |
|---|---|---|---|---|
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | 29 | 7.26×10−6 | TNF, FOXK1, ONECUT2, NR6A1, FOXK2, TP63, RORA, MED20, WT1, HOXA1, NPAS1, SQSTM1, MED26, HSF4, RARB, DGKQ, KLF9, EPAS1, NR4A1, TEAD2, NR0B1, IL22, SP2, ETS1, JUN, MNX1, TFAP2E, KLF4, NFIB |
| GO:0045935 | Positive regulation of nucleic acid metabolic process | 25 | 3.53×10−5 | TNF, FOXK1, ONECUT2, TP63, ABCA1, RORA, WT1, HOXA1, SQSTM1, H2AFX, RARB, HSF4, EPAS1, TAF8, ESRRG, NR4A1, TEAD2, IL22, EREG, IRF6, ETS1, JUN, TFAP2E, KLF4, NFIB |
| GO:0045893 | Positive regulation of transcription | 21 | 5.04×10−5 | TNF, EPAS1, FOXK1, TAF8, ONECUT2, ESRRG, TP63, NR4A1, TEAD2, RORA, IL22, WT1, HOXA1, SQSTM1, ETS1, JUN, RARB, HSF4, TFAP2E, KLF4, NFIB |
| GO:0051254 | Positive regulation of RNA metabolic process | 21 | 5.72×10−5 | TNF, EPAS1, FOXK1, TAF8, ONECUT2, ESRRG, TP63, NR4A1, TEAD2, RORA, IL22, WT1, HOXA1, SQSTM1, ETS1, JUN, RARB, HSF4, TFAP2E, KLF4, NFIB |
| GO:0051173 | Positive regulation of nitrogen compound metabolic process | 25 | 5.82×10−5 | TNF, FOXK1, ONECUT2, TP63, ABCA1, RORA, WT1, HOXA1, SQSTM1, H2AFX, RARB, HSF4, EPAS1, TAF8, ESRRG, NR4A1, TEAD2, IL22, EREG, IRF6, ETS1, JUN, TFAP2E, KLF4, NFIB |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | 18 | 6.37×10−5 | TNF, EPAS1, ONECUT2, TP63, NR4A1, TEAD2, RORA, IL22, WT1, HOXA1, SQSTM1, ETS1, JUN, RARB, HSF4, TFAP2E, KLF4, NFIB |
| GO:0009891 | Positive regulation of biosynthetic process | 26 | 7.16×10−5 | TNF, FOXK1, ONECUT2, TP63, APOC2, ABCA1, RORA, WT1, TGFβ2, HOXA1, SQSTM1, RARB, HSF4, EPAS1, TAF8, ESRRG, NR4A1, TEAD2, IL22, EREG, IRF6, ETS1, JUN, TFAP2E, KLF4, NFIB |
| GO:0031328 | Positive regulation of cellular biosynthetic process | 25 | 1.51s10−4 | TNF, FOXK1, ONECUT2, TP63, APOC2, ABCA1, RORA, WT1, HOXA1, SQSTM1, RARB, HSF4, EPAS1, TAF8, ESRRG, NR4A1, TEAD2, IL22, EREG, IRF6, ETS1, JUN, TFAP2E, KLF4, NFIB |
| GO:0010557 | Positive regulation of macromolecule biosynthetic process | 24 | 1.97×10−4 | TNF, EPAS1, FOXK1, TAF8, ONECUT2, ESRRG, TP63, NR4A1, TEAD2, RORA, IL22, WT1, TGFβ2, HOXA1, EREG, IRF6, SQSTM1, ETS1, JUN, RARB, HSF4, TFAP2E, KLF4, NFIB |
| GO:0010628 | Positive regulation of gene expression | 22 | 2.62×10−4 | TNF, EPAS1, FOXK1, TAF8, ONECUT2, ESRRG, TP63, NR4A1, TEAD2, RORA, IL22, WT1, HOXA1, IRF6, SQSTM1, ETS1, JUN, RARB, HSF4, TFAP2E, KLF4, NFIB |