Table 3.
Association results by ethnic group.
| SNP | Nearest Gene | European Americans | Hispanic Americans | African Americans | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||||
| Model 1 | Model 2 | Model 1 | Model 2 | Model 1 | Model 2 | ||||||||
|
| |||||||||||||
| beta (SE) |
p | beta (SE) |
p | beta (SE) |
p | beta (SE) |
p | beta (SE) |
p | beta (SE) |
p | ||
| rs2444217 | ADCY9 | −0.004 (0.006) |
0.51 | −0.003 (0.005) |
0.60 | −0.030 (0.012) |
1.26E-02 | −0.028 (0.011) |
1.29E-02 | −4.00E-03 (0.015) |
0.77 | −0.005 (0.014) |
0.71 |
| rs10767664 | BDNF | 0.003 (0.007) |
0.65 | −0.001 (0.007) |
0.91 | −0.015 (0.015) |
0.32 | −0.020 (0.014) |
0.15 | 0.032 (0.025) |
0.19 | 0.032 (0.025) |
0.20 |
| rs13078807 | CADM2 | 0.015 (0.007) |
0.03 | 0.011 (0.007) |
0.11 | −0.014 (0.016) |
0.40 | −0.015 (0.016) |
0.33 | ||||
| rs7647305 | ETV5 | −0.008 (0.007) |
0.26 | −0.009 (0.007) |
0.18 | −0.018 (0.015) |
0.23 | −0.020 (0.014) |
0.17 | 0.004 (0.013) |
0.77 | −0.002 (0.012) |
0.85 |
| rs7138803 | FAIM2 | 0.006 (0.006) |
0.26 | 0.004 (0.006) |
0.52 | −0.016 (0.013) |
0.22 | −0.016 (0.013) |
0.21 | 0.002 (0.017) |
0.93 | −0.003 (0.016) |
0.84 |
| rs887912 | FANCL | −0.003 (0.006) |
0.65 | −0.006 (0.006) |
0.32 | −0.010 (0.015) |
0.53 | −0.012 (0.015) |
0.42 | ||||
| rs2112347 | FLJ3577 | −0.003 (0.006) |
0.55 | −0.005 (0.006) |
0.41 | −0.008 (0.012) |
0.52 | −0.011 (0.012) |
0.35 | ||||
| rs9939609 | FTO | 0.004 (0.006) |
0.50 | −0.007 (0.006) |
0.20 | 0.008 (0.012) |
0.54 | −0.005 (0.012) |
0.66 | 0.005 (0.012) |
0.68 | 0.004 (0.012) |
0.76 |
| rs10938397 | GNPDA2 | 0.005 (0.006) |
0.37 | 0.003 (0.005) |
0.55 | 0.005 (0.012) |
0.71 | 0.005 (0.012) |
0.68 | 0.006 (0.015) |
0.67 | −0.003 (0.014) |
0.83 |
| rs12444979 | GPRC5B | −0.004 (0.008) |
0.58 | −0.007 (0.008) |
0.36 | 0.030 (0.020) |
0.12 | 0.017 (0.019) |
0.36 | ||||
| rs29941 | KCTD15 | −0.004 (0.006) |
0.54 | −0.005 (0.006) |
0.34 | 0.017 (0.012) |
0.17 | 0.013 (0.012) |
0.28 | ||||
| rs867559 | LMX1B | 0.005 (0.007) |
0.48 | 0.001 (0.007) |
0.86 | 0.033 (0.012) |
5.62E-03 | 0.028 (0.011) |
1.33E-02 | −0.001 (0.014) |
0.93 | −1.00E-04 (0.013) |
0.99 |
| rs2890652 | LRP1B | 0.011 (0.008) |
0.15 | 0.008 (0.007) |
0.26 | 0.029 (0.017) |
0.09 | 0.027 (0.016) |
0.09 | −0.003 (0.016) |
0.86 | −0.012 (0.016) |
0.45 |
| rs10968576 | LRRN6C | 0.006 (0.006) |
0.33 | 0.001 (0.006) |
0.85 | −0.010 (0.014) |
0.45 | −0.014 (0.013) |
0.30 | ||||
| rs2605100 | LYPLAL1 | −0.002 (0.006) |
0.72 | −0.003 (0.006) |
0.66 | 0.0077 (0.012) |
0.54 | 0.005 (0.012) |
0.69 | 0.002 (0.019) |
0.91 | 0.009 (0.019) |
0.65 |
| rs543874 | LZTR2 | 0.009 (0.007) |
0.21 | 0.002 (0.007) |
0.78 | −0.009 (0.015) |
0.54 | −0.016 (0.014) |
0.27 | −0.022 (0.015) |
0.13 | −0.028 (0.014) |
0.05 |
| rs1424233 | MAF | 0.011 (0.006) |
0.05 | 0.009 (0.005) |
0.09 | 0.002 (0.012) |
0.88 | 0.003 (0.012) |
0.81 | −0.026 (0.013) |
0.05 | −0.024 (0.013) |
0.06 |
| rs2241423 | MAP2K5 | 0.006 (0.006) |
0.37 | 0.002 (0.006) |
0.79 | −0.011 (0.012) |
0.34 | −0.009 (0.011) |
0.43 | 0.012 (0.013) |
0.36 | 0.006 (0.012) |
0.62 |
| rs12970134 | MC4R | 0.004 (0.006) |
0.55 | −0.004 (0.006) |
0.55 | 0.013 (0.015) |
0.40 | 0.007 (0.015) |
0.64 | ||||
| rs571312 | MC4R | 0.001 (0.006) |
0.89 | −0.007 (0.006) |
0.23 | 0.007 (0.016) |
0.66 | −0.003 (0.015) |
0.86 | ||||
| rs545854 | MSRA | 0.005 (0.007) |
0.47 | 0.002 (0.007) |
0.75 | −0.001 (0.014) |
0.92 | −0.002 (0.013) |
0.90 | −0.022 (0.029) |
0.44 | −0.027 (0.028) |
0.34 |
| rs3817334 | MTCH2 | 0.013 (0.006) |
0.02 | 0.008 (0.005) |
0.13 | −0.003 (0.012) |
0.77 | −0.009 (0.011) |
0.43 | 0.003 (0.014) |
0.82 | 0.001 (0.014) |
0.96 |
| rs4771122 | MTIF3 | −0.002 (0.007) |
0.79 | −0.004 (0.006) |
0.50 | 0.016 (0.015) |
0.28 | 0.010 (0.014) |
0.49 | ||||
| rs1077393 | NCR3/BAT2 | −0.001 (0.005) |
0.81 | −0.002 (0.005) |
0.70 | −0.004 (0.012) |
0.71 | −0.001 (0.011) |
0.90 | −0.016 (0.013) |
0.22 | −0.017 (0.013) |
0.18 |
| rs2568958 | NEGR1 | 0.015 (0.006) |
0.01 | 0.011 (0.006) |
0.04 | 0.002 (0.013) |
0.90 | 0.004 (0.012) |
0.74 | ||||
| rs1805081 | NPC1 | 0.001 (0.006) |
0.84 | −0.002 (0.005) |
0.65 | 0.034 (0.013) |
1.00E-02 | 0.027 (0.013) |
0.03 | −0.002 (0.022) |
0.92 | 0.009 (0.022) |
0.68 |
| rs10146997 | NRXN3 | −0.003 (0.007) |
0.63 | −0.001 (0.007) |
0.82 | −0.006 (0.014) |
0.66 | −0.001 (0.014) |
0.93 | 0.002 (0.013) |
0.87 | −0.003 (0.013) |
0.81 |
| rs206936 | NUDT3 | 0.004 (0.007) |
0.55 | 0.001 (0.007) |
0.92 | 0.013 (0.012) |
0.25 | 0.012 (0.011) |
0.30 | 0.013 (0.013) |
0.30 | 0.011 (0.012) |
0.38 |
| rs713586 | POMC | 0.004 (0.006) |
0.44 | −0.001 (0.005) |
0.89 | −0.001 (0.012) |
0.94 | −0.001 (0.011) |
0.95 | −0.025 (0.017) |
0.14 | −0.023 (0.016) |
0.16 |
| rs11847697 | PRKD1 | −0.016 (0.012) |
0.21 | −0.024 (0.012) |
0.05 | 0.038 (0.022) |
0.08 | 0.031 (0.021) |
0.14 | ||||
| rs4712652 | PRL | 0.003 (0.006) |
0.61 | −0.001 (0.007) |
0.89 | −0.015 (0.012) |
0.20 | −0.017 (0.011) |
0.14 | 0.014 (0.013) |
0.30 | 0.016 (0.013) |
0.23 |
| rs1555543 | PTBP2 | 0.007 (0.006) |
0.18 | 0.003 (0.005) |
0.58 | −0.011 (0.012) |
0.37 | −0.014 (0.011) |
0.22 | ||||
| rs10508503 | PTER | 0.002 (0.010) |
0.86 | −0.004 (0.010) |
0.67 | 0.013 (0.025) |
0.60 | 0.017 (0.024) |
0.47 | 0.018 (0.051) |
0.73 | 0.027 (0.050) |
0.58 |
| rs2287019 | QPCTL | 0.001 (0.007) |
0.89 | −0.004 (0.007) |
0.56 | 0.019 (0.018) |
0.28 | 0.018 (0.017) |
0.28 | ||||
| rs4929949 | RPL27A | 0.007 (0.005) |
0.21 | 0.006 (0.005) |
0.29 | 0.004 (0.012) |
0.71 | 0.005 (0.011) |
0.67 | ||||
| rs10913469 | SEC16B | 0.009 (0.007) |
0.17 | 0.004 (0.007) |
0.57 | −0.018 (0.015) |
0.23 | −0.023 (0.014) |
0.10 | −0.032 (0.014) |
0.02 | −0.036 (0.013) |
6.81E-03 |
| rs4788102 | SH2B1 | 0.021 (0.006) |
2.24E-04 | 0.017 (0.005) |
1.66E-03 | −0.002 (0.012) |
0.88 | −0.004 (0.011) |
0.70 | −0.027 (0.014) |
0.05 | −0.031 (0.013) |
0.02 |
| rs7359397 | SH2B1/APOB48 | 0.018 (0.006) |
9.77E-04 | 0.015 (0.005) |
4.57E-03 | −0.002 (0.012) |
0.85 | −0.002 (0.011) |
0.71 | −0.013 (0.022) |
0.56 | −0.018 (0.021) |
0.41 |
| rs13107325 | SLC39A8 | −0.003 (0.010) |
0.79 | −0.008 (0.010) |
0.44 | 0.011 (0.030) |
0.72 | 0.006 (0.029) |
0.84 | ||||
| rs987237 | TFAP2B | 0.010 (0.007) |
0.18 | 0.001 (0.007) |
0.84 | 0.006 (0.013) |
0.62 | 0.001 (0.012) |
0.97 | −0.005 (0.020) |
0.80 | −0.004 (0.020) |
0.86 |
| rs3810291 | TMEM160 | −0.004 (0.006) |
0.45 | −0.005 (0.006) |
0.36 | −0.005 (0.012) |
0.69 | −0.007 (0.011) |
0.55 | 0.002 (0.015) |
0.90 | 0.003 (0.015) |
0.87 |
| rs6548238 | TMEM18 | 0.009 (0.007) |
0.20 | −0.001 (0.007) |
0.86 | −0.012 (0.017) |
0.48 | −0.020 (0.016) |
0.23 | −0.025 (0.020) |
0.21 | −0.031 (0.020) |
0.11 |
| rs1514175 | TNNI3K | 0.000 (0.006) |
0.97 | −0.003 (0.005) |
0.54 | 0.019 (0.012) |
0.11 | 0.016 (0.011) |
0.14 | ||||