. Author manuscript; available in PMC: 2017 Jun 1.

Published in final edited form as: Handb Exp Pharmacol. 2014;221:203–229. doi: 10.1007/978-3-642-41588-3_10

Table 2.

m-Conopeptide activity matrix: peptides that best discriminate between given pairs of Nav1-isoforms, as revealed by their discrimination index (DI) values

Nav	1.1	1.2	1.3	1.4	1.5	1.6	1.7
1.1		SIIIA	MIIIA	TIIIA	CnIIIA	SIIIA	KIIIA
1.1		2.3	0.5	2.3	0.3	1.2	0.0
1.2	GIIIA		PIIIA	GIIIA	GIIIA	GIIIA	GIIIA
1.2	1.8		−0.7	3.0	−0.8	1.4	−0.8
1.3	GIIIA	KIIIA		SxIIIA	CnIIIA	SxIIIA	KIIIA
1.3	2.6	3.2		4.2	0.2	2.2	1.4
1.4	KIIIA	KIIIA	MIIIA		CnIIIA	KIIIA	KIIIA
1.4	−0.5	1.3	−1.4		−1.4	−0.4	−0.5
1.5	KIIIA	KIIIA	BuIIIB	TIIIA		KIIIA	KIIIA
1.5	3.0	4.8	1.7	4.3		3.1	3.0
1.6	SmIIIA	TIIIA	BuIIIA	TIIIA	CnIIIA		KIIIA
1.6	1.6	2.7	1.1	3.7	0.0		−0.1
1.7	PIIIA	BuIIIB	BuIIIB	BuIIIB	CnIIIA	PIIIA
1.7	2.9	3.9	2.7	4.4	1.1	3.0