Figure 4.
Superimposition of the catalytic cavities of LSD1/KDM1A (cyan) and LSD2/KDM1B (magenta) in complex with 2-PCPA. The FAD•2-PCPA adduct in the LSD1•2-PCPA complex (PDB ID: 2Z5U) is depicted in blue, and that in the LSD2•2-PCPA complex (PDB ID: 4GUU) is depicted in red.