Figure 4.

Immune activation by commercially available ultrapure alginate and alginate as shown in the previous graphs. The right bar indicated our own procedure of purification, i.e., how it is performed at the University Medical Center Groningen (UMCG).Values are presented as mean ± SD. LPS was used as a positive control, which induced a NF-κB activation of 2.070 ± 0.135. The difference between our purification proceeding and the one from Laboratoires Brothier was statistically significant (p < 0.01, **).