Figure 4.

After a 5-s sonication treatment, scanning electron microscopy images of regenerated layers obtained from inorganic pyrophosphate (PP_i)–stabilized supersaturated calcium phosphate (CaP) solution in the presence (A) and the absence of 0.04 mg/mL leucine-rich amelogenin peptide (LRAP) (B). The mineral layers formed in the presence of LRAP adhered strongly to the enamel surface and were unaffected by sonication (A). In contrast, the mineral layer formed in the absence of LRAP was readily removed by sonication (B).