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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: J Mol Cell Cardiol. 2016 Aug 18;99:151–161. doi: 10.1016/j.yjmcc.2016.08.011

Fig. 5.

Fig. 5

GS-458967 can effectively attenuate APD prolongation by ATX-II in rabbit ventricular myocytes. (A) Experimental data from two distinct data sets from rabbit ventricular myocytes showing drug free conditions (left), the effect of 3 nM ATX-II (middle) and the combination of 3 nM ATX-II with 0.3 μM GS-458967 (right). (B) Simulated effects on virtual rabbit ventricular myocyte showing drug free (left), simulated effect of ATX-II (middle) and ATX-II with co-treatment with GS-458967 0.3 μM (right).