Fig. 1.

Custom cyclic strain bioreactor. (A) Custom bioreactor designed with 24 individual wells with static loading posts and moveable rake controlled by a programmable linear actuator. (B) Scaffolds (with fiduciary marks) embedded into hollow PLA end-blocks that can be attached on either end to the static loading post and movable rake within the bioreactor. (C) SEM image of aligned scaffold pore microstructure. Scale bar: 1 mm. (D) Superimposition of measured scaffold deformation in response to a range of system applied cyclic strain amplitudes (5–20 %, all 1 Hz). Scaffold deformation is shown as mean ± SEM.