Fig 6. Kaplan-Meier curves of heart allograft survival in mice inoculated with cognate allogeneic SPL or PerC B cells.
We investigated the effect allogeneic PerC B cells on prolonging the survival of cognate allografted hearts in a mouse model of heart transplantation. B6 mice were intravenously injected with or without Balb/c SPL or PerC B cells (10 x 106 cells/mouse; n = 7 per group) and were transplanted with the heterotopic hearts of Balb/c mice at 2 weeks after the B cell inoculation. Data are presented as percentage graft survival (**p < 0.01 vs mice in other groups).