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. 2017 May 19;11(5):e0005595. doi: 10.1371/journal.pntd.0005595

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© 2017 Koslowski et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — Representative images of mouse livers and spleens are shown: uninfected mice (naive), bisexual infected control (mf/mf), infected bisexual control (-/mf), primary infection with male cercariae (m/mf), primary infection with female cercariae (f/mf). (A) Macroscopic assessment of livers and spleens reveals less pronounced organ changes in group f/mf than in mf/mf, -/mf and m/mf. (B) Reduction in liver and spleen indexes in group f/mf indicates that a primary infection with female S. mansoni cercariae has a beneficial effect on disease progression. Data are presented as mean ± SD. (C) Serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (AP) are presented as mean ± SD. (D) Numbers of worm pairs and hepatic eggs are given as mean ± SD. P≤0.05 was considered to be statistically significant.