Fig 7. Primary infection with female S. mansoni cercariae induces Ctla4 expression in bisexually challenged mice.

Gene expression values of Arg1, Retnla, Foxp3 and Ctla4 at week 19 were normalized to the endogenous reference gene GAPDH and presented as relative expression values to the naive control. Values are given as mean ± SD. p≤0.05 was considered to be statistically significant.