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. 2017 Jun 1;12(6):e0178391. doi: 10.1371/journal.pone.0178391

Fig 6. Adult and adolescent expression of syntaxin binding protein 1 (STXBP1).

Fig 6

(A) Representative 3D plot of STXBP expression in adult (left) and adolescent (right) mice for Spot #20. (B) Standardized abundance (log) of STXBP1 (Spot 20) demonstrating higher expression in adults versus adolescents. (C) Representative 3D plot of STXBP1 expression in adult (left) and adolescent (right) mice for Spot #79. (D) Standardized abundance (log) of STXBP1 (Spot 79) demonstrating higher expression in adults versus adolescents. (E) Representative gel image of a Western blot for STXBP1 expression to confirm 2D-DIGE changes. (F) Quantification of Western blot results, confirming reduced expression of STXBP1 (normalized to actin) in adolescents as compared to adults. (G) STXBP1 expression was greater in adults in dStr, NAc, M1, Amy, and VTA. Top, representative gel images for each brain region; bottom, quantification of Western blots for each brain region. (*** indicates p≤0.001, **** indicates p≤0.0001.)