Skip to main content
. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Biochemistry. 2015 Dec 3;54(49):7178–7192. doi: 10.1021/acs.biochem.5b01074

Table 1.

NO release (% of theoretical maximum) from DD-1, DD-2, and DD-3 in the presence of L-cysteine or human serum

Compd Matrix %NO Release
1 hr 2 hrs 4 hrs 8 hrs
DD-1 L-Cys 3.8 ± 0.4 5.9 ± 0.3 8.8 ± 0.4 9.3 ± 0.3
Serum 10.0± 0.1 9.7± 0.3 8.5± 1.0 10.4± 0.2
DD-2 L-Cys 3.5 ± 0 4.2 ± 0.1 5.2 ± 0.4 5.3 ± 0.3
Serum 2.3± 2.0 7.0± 1.8 5.8± 0 5.1± 0.04
DD-3 L-Cys 1.8 ± 0.07 3.1 ± 0.2 4.7 ± 0.07 5.1 ± 0.1
Serum 41.5± 0.2 45.7± 1.4 50.6± 1.9 52.5± 0.5

The experiments were performed in duplicate or triplicate. All compounds were solubilized in DMSO (2%). Control experiments without test compound also contain 2% DMSO