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Effects of compounds on Hb oxygen affinity with clarified Hb (2 mM).
| Compound | ΔP50 (mmHg) | |||
|---|---|---|---|---|
| 1h | 2h | 4h | 8h | |
| RSR13 | 3.8 | 4.65 | 4.48 | 3.96 |
| DD-1 | -0.22 | 0.28 | 0.18 | 1.25 |
| DD-2 | -0.07 | 0.18 | 0.28 | 1.70 |
| DD-3 | -0.07 | 0.09 | 0.0 | 0.81 |
ΔP50 = (P50 control – P50 sample). All compounds were solubilized in DMSO (2%). Control experiments without test compound also contain 2% DMSO
