Table 1. Study subjects.
| Non-diseased group | Diseased group | |
|---|---|---|
| (n = 59) | (n = 109) | |
| Age (years) | 41.7 ± 9.4 | 53.4 ± 15.9 |
| Gender (male, %) | 64.4 | 68.8 |
| Body height (cm) | 167.1 ± 7.5 | 166.4 ± 8.9 |
| Body weight (kg) | 65.3 ± 16.1 | 69.5 ± 17.1 |
| Body mass index (kg/m2) | 23.3 ± 5.3 | 24.8 ± 4.2 |
| TC (mg/dL) | 187.0 ± 24.3 [124.1–237.6] | 200.5 ± 38.9 [110.0–325.6] |
| LDL-Crmp (mg/dL) | 109.7 ± 20.9 [60.0–159.4] | 121.2 ± 35.9 [51.7–230.0] |
| HDL-Crmp (mg/dL) | 60.7 ± 12.7 [38.2–98.9] | 51.8 ± 13.3 [21.8–88.7] |
| TG (mg/dL) | 115.2 ± 45.3 [30.8–194.2] | 195.6 ± 144.6 [32.9–880.4] |
| Non-fasting subjects (%) | 72.9 | 39.4 |
| Time since last meal (h)1) | 2.8 ± 1.9 | 2.6 ± 1.8 |
| Hypolipidemic agents taken (statin) (%) | 0.0 | 56.9 (39.4) |
| Dyslipidemia (%)2) | 0.0 | 88.1 |
| Type I/V | 0.0 | 0.9/1.8 |
| Type IIa/IIb (FH) | 0.0 (0.0) | 64.2 (12.8) |
| Type III | 0.0 | 0.9 |
| Type IV | 0.0 | 20.2 |
| Cardiovascular disease (%) | 0.0 | 21.1 |
| Diabetes mellitus (%) | 0.0 | 8.3 |
| Fatty liver/alcoholic liver injury (%) | 0.0 | 1.8 |
| Renal disease (%) | 0.0 | 1.8 |
| Hyperthyroidism (%) | 0.0 | 0.9 |
Data are presented as means ± SD [minima to maxima], or as percentages.
TC, total cholesterol; LDL-C, low-density lipoprotein-cholesterol; HDL-C, high-density lipoprotein-cholesterol; RMP, reference measurement procedures; TG, triglyceride; FH, familial hypercholesterolemia
1)
Values were calculated using the postprandial samples.
2)
Phenotypes were determined by analysis of the pre-treatment lipid profiles in the fasting state, using the classification of Frederickson.